Certified Registered Nurse Anesthetist (CRNA) Practice Exam

What is a potential effect of succinylcholine related to pressure in the body?

1. Decreased intraocular pressure

2. Increased intracranial pressure

3. Increased intra-abdominal pressure

4. Decreased lower esophageal sphincter tone

The correct answer is: Increased intracranial pressure

Succinylcholine, a depolarizing neuromuscular blocker, is known for its rapid onset and short duration of action, making it useful in various anesthetic procedures, particularly for intubation. One of the notable effects of succinylcholine is its potential to increase intracranial pressure. The mechanism behind this involves the drug’s ability to induce muscle fasciculations, which can stimulate sympathetic outflow and possibly cause a transient increase in blood pressure and cerebral blood flow. This response contributes to a temporary rise in intracranial pressure, especially in patients with compromised intracranial compliance or conditions that may already elevate intracranial pressure. This information is vital for CRNAs to consider when administering succinylcholine, particularly in patients with head injuries or existing intracranial hypertension. Monitoring and managing intracranial pressure is crucial in these situations to avoid exacerbating any potential harm. In contrast, other options reflect different physiological effects and are not associated with succinylcholine's role in increasing intracranial pressure. Understanding these nuances helps practitioners make informed decisions during anesthesia management.