Certified Registered Nurse Anesthetist (CRNA) Practice Exam

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Which of the following best describes the duration of action for Etomidate?

  1. 1 to 2 minutes

  2. 4 to 10 minutes

  3. 30 to 60 minutes

  4. 2 to 4 hours

The correct answer is: 4 to 10 minutes

Etomidate is a short-acting intravenous anesthetic commonly used for induction due to its rapid onset and relatively brief duration of action. The primary characteristic of Etomidate is that it has a duration of action that typically ranges from 4 to 10 minutes. This duration allows for quick recovery after the drug is administered, making it particularly useful in situations where a fast-acting anesthetic is desirable. Etomidate is metabolized rapidly by the liver and has a high clearance rate, contributing to its short duration. Additionally, it provides the advantage of minimal cardiovascular and respiratory depression, which is important for maintaining stability in patients undergoing procedures. The options representing other durations do not reflect the pharmacokinetics of Etomidate. Therefore, understanding its mechanism and characteristics is crucial in determining its appropriate use during anesthesia induction.